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BITTER TASTE MASKED ORAL THIN FILM FORMULATION OF SILDENAFIL CITRATE

机译:枸DEN酸西地那非的口感苦涩的口感口香糖薄膜配方

摘要

Bitter taste masked oral thin film formulations of sildenafil citrate that rapidly dissolve in the oral cavity, are disclosed. By preparing the fast-dissolving oral thin film of compositions, comprising bitter tasting sildenafil citrate and the bitter taste masking agent of sodium hydroxide, sodium bicarbonate or the mixtures thereof, this invention provides a formulation of an excellent fast-dissolving oral thin film which can mask the bitter taste of sildenafil citrate and thus mitigating an unpleasant feelings at time of drug administration.
机译:公开了在口腔中迅速溶解的柠檬酸西地那非的具有苦味掩盖的口腔薄膜制剂。通过制备包含苦味柠檬酸西地那非和氢氧化钠,碳酸氢钠或其混合物的苦味掩盖剂的组合物的快速溶解口腔薄膜,本发明提供了一种优异的快速溶解口腔薄膜的制剂,该制剂可以掩盖了枸sil酸西地那非的苦味,从而减轻了给药时的不适感。

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