MicroRNA-based methods for the diagnosis of colon, pancreatic, prostate, and stomach cancer

摘要

The present invention provides novel methods for the diagnosis of solid cancers selected from the group consisting of colon, pancreas, prostate and stomach cancer. The methods comprise measuring the level of at least a first miR-223 gene product. When the cancer is colon cancer, at least one additional miR gene product is used to diagnose colon cancer, the at least one additional miR gene product being selected from the group consisting of: miR-21, miR-17-5p, miR-191, miR-29b-2, miR-128b, miR-24-1, miR-24-2, miR-155, miR-20a, miR-107, miR-32, miR-30c, miR-221, miR-106a, miR-10a, miR-203, miR-126*, miR-24-2, miR-99b prec, miR-213, miR-150, miR-9-3 and combinations thereof.