EFFECT OF ORALLY ADMINISTERED DIPTERINYL CALCIUM PENTAHYDRATE (DCP) ON ORAL GLUCOSE TOLERANCE IN DIO MICE

摘要

Provided herein are methods of treating diabetes comprising administering to a subject a therapeutically effective amount of dipterinyl calcium pentahydrate (DCP). Dipterinyl calcium pentahydrate (DCP) is a molecular entity whose structure is based upon the endogenous substance pterin, has effects on glucose tolerance and other measures in vivo were determined in mice fed a high-fat diet to induce obesity and insulin resistance. DCP was found to significantly improve oral glucose tolerance (OGTT) in female DIO mice,C57BL/67.