METHOD FOR THE REALISATION OF A BIOCOMPATIBLE BONE IMPIANT COMPRISING GRANULAR ELEMENTS AND A BIOREABSORBABLE BIOPOLYMER GEL AND BIOCOMPATIBLE BONE IMPIANT THUS OBTAINED

摘要

Method for providing a biocompatible bone implant adapted to fill a bone cavity or lacuna comprising the steps of providing granular elements in form of granules and/or granule aggregates, providing at least one primary polymeric solution comprising a biopolymer, at least partly coating the granular elements with the primary polymeric solution, obtaining coated granular elements comprising a biopolymer coating, providing a cross-linking solution, dipping the coated granular elements in the cross-linking solution, waiting a period of time referred to as "jellification time" comprised between 30 seconds and 1 hour, in which during said waiting step there occurs the cross-linking of the biopolymer coating of the granular elements with the cross-linking solution and the jellification of the coating, with the aim of obtaining a cohesive biocompatible implant comprising granular elements and a bio-reabsorbable biopolymer gel; biocompatible bone implant obtained through such method.