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Peptide vaccines comprising Seq Id 101, 80 or 100 for cancers expressing tumor-associated antigens
Peptide vaccines comprising Seq Id 101, 80 or 100 for cancers expressing tumor-associated antigens
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机译:包含Seq Id 101、80或100的肽疫苗,用于表达与肿瘤相关的抗原的癌症
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摘要
The present invention provides peptides having an amino acid sequence as set forth in SEQ ID NO: 101, 80 or 100 as well as peptides having the above-mentioned amino acid sequences in which 1, 2, or several (e.g., up to 5) amino acids are substituted, deleted, or added, provided the peptides possess cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing a disease associated with over-expression of the ECT2, e.g. cancers containing as an active ingredient one or more of these peptides. The peptides of the present invention find further utility as vaccines.
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机译:本发明提供具有SEQ ID NO:101、80或100所示氨基酸序列的肽,以及具有上述氨基酸序列的肽,其中1、2或几个(例如,最多5个)如果肽具有细胞毒性T细胞诱导性,则取代,缺失或添加氨基酸。本发明还提供了用于治疗或预防与ECT2过表达有关的疾病的药物,例如ECT2。含有一种或多种这些肽作为有效成分的癌症。发现本发明的肽进一步用作疫苗。
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