Modulation of G protein-mediated signal transduction pathways

摘要

The present invention relates to methods for regulating signal transduction pathways activated by cigarette smoke by modulating, particularly by agonizing or antagonizing, the function and/or activity of a GPCR, which is directly modulated by cigarette smoke. The invention further relates to methods for assessing cigarette smoke or fractions thereof which directly modulates the activity of a GPCR..