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ANTIMICROBIAL PEPTIDES AND PEPTIDE DERIVATIVES DERIVED FROM ONCOPELTUS FASCIATUS

机译：虾粉菌的抗菌肽和肽衍生物

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摘要

The present invention relates to a antimicrobial peptide or peptide derivative comprising the following sequence: Sub1-X1-D2-K3-P4-P5-Y6-L7-P8-R9-P10-X2-P12-P13-R14-X3-T16-P17-N18-N19-X4-Sub2. The invention further relates to multimers comprising said peptides or peptide derivatives. Moreover, the invention provides a peptide or peptide derivative for use in the treatment of a disease. The peptide or peptide derivative may also be used in the screening for novel antimicrobial compounds.

机译：本发明涉及包含以下序列的抗微生物肽或肽衍生物：Sub1-X1-D2-K3-P4-P5-Y6-L7-P8-R9-P10-X2-P12-P13-R14-X3-T16- P17-N18-N19-X4-Sub2。本发明进一步涉及包含所述肽或肽衍生物的多聚体。此外，本发明提供了用于治疗疾病的肽或肽衍生物。该肽或肽衍生物也可用于筛选新型抗微生物化合物。

著录项

公开/公告号EP2575852A1

专利类型
公开/公告日2013-04-10

原文格式PDF
申请/专利权人 AMP THERAPEUTICS GMBH;UNIVERSITÄT LEIPZIG;
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申请/专利号EP20110727138
发明设计人 HOFFMANN RALF;KNAPPE DANIEL;
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申请日2011-05-27
分类号A61K38/10;C07K14/435;C12N15;
国家 EP
入库时间 2022-08-21 16:30:09

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