首页> 外国专利> GENE EXPRESSION MARKERS FOR PREDICTING RESPONSE TO INTERLEUKIN-6 RECEPTOR-INHIBITING MONOCLONAL ANTIBODY DRUG TREATMENT

GENE EXPRESSION MARKERS FOR PREDICTING RESPONSE TO INTERLEUKIN-6 RECEPTOR-INHIBITING MONOCLONAL ANTIBODY DRUG TREATMENT

机译:基因表达标志物用于预测对白介素-6受体抑制性单克隆抗体药物治疗的反应

摘要

This invention provides methods, compositions, and kits relating to gene product biomarkers where gene expression levels are correlated with therapeutic response of rheumatoid arthritis patients to treatment with an IL-6 receptor antagonist, such as an IL6-R antibody. The methods, compositions, and kits of the invention can be used to identify rheumatoid arthritis patients who are likely, or not likely, to respond to IL-6 receptor antagonist treatments.
机译:本发明提供了与基因产物生物标志物有关的方法,组合物和试剂盒,其中基因表达水平与类风湿性关节炎患者对IL-6受体拮抗剂(例如IL6-R抗体)的治疗反应相关。本发明的方法,组合物和试剂盒可用于鉴定可能或不太可能对IL-6受体拮抗剂治疗有反应的类风湿关节炎患者。

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