首页> 外国专利> BLOOD LIPID-REGULATING RED YEAST LIGUSTICUM CHUANXIONG PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR

BLOOD LIPID-REGULATING RED YEAST LIGUSTICUM CHUANXIONG PHARMACEUTICAL COMPOSITION AND PREPARATION METHOD THEREFOR

机译:血脂调节型红曲川G 药物的组成及制备方法

摘要

Disclosed are a pharmaceutical composition having blood lipid-regulating effects (particularly for treatment of hypertriglyceridemia) and a preparation method therefor; also disclosed is a pharmaceutical use of the pharmaceutical composition. The pharmaceutical composition of the present invention combines red yeast and Ligusticum chuanxiong with each other to produce a synergistic effect and to provide efficacy for clearance of moisture and mucus, for blood circulation, and for spleen-caring and digestion, is capable of reducing total cholesterol in blood, of increasing high-density lipoprotein, and of reducing low-density lipoprotein content, is particularly conspicuous in expression of a triglyceride reduction effect, and allows for significant treatment of hypertriglyceridemia. The preparation process of the present invention is reasonable in that not only the content of the active ingredient Lovastatin in the red yeast is increased, but also the active ingredients of medicaments in a prescription are preserved, thus giving full play to the effects of the medicaments. The content of Lovastatin serves as a quality control indicator for the preparation of the present invention, while the quality of the preparation is stable and controllable.
机译:本发明公开了一种具有调节血脂作用的药物组合物(特别是用于治疗高甘油三酯血症)及其制备方法。还公开了药物组合物的药物用途。本发明的药物组合物将红酵母和川Li(Igusticum chuanxiong)相互结合,以产生协同作用并提供清除水分和粘液,血液循环以及健脾和消化的功效。能够降低血液中的总胆固醇,增加高密度脂蛋白和降低低密度脂蛋白含量,在降低甘油三酸酯的效果上尤为突出,并可以有效治疗高甘油三酯血症。本发明的制备方法是合理的,因为不仅增加了红色酵母中活性成分洛伐他汀的含量,而且还保留了处方中药物的活性成分,从而充分发挥了药物的作用。 。洛伐他汀的含量用作本发明制剂的质量控制指标,而制剂的质量稳定且可控。

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