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ORAL ADMINISTRATION FORMS FOR CONTROLLED RELEASE OF RIFAMPICIN OR OTHER ANTIBIOTICS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT
ORAL ADMINISTRATION FORMS FOR CONTROLLED RELEASE OF RIFAMPICIN OR OTHER ANTIBIOTICS FOR THE TREATMENT OF BACTERIAL INFECTIONS AND INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT
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机译:利福平或其他抗菌药物可控释放的口服制剂,用于治疗胃肠道炎和细菌性感染
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摘要
Oral administration forms are described for the controlled release of an antibiotic selected from the group consisting of rifampicin, rifabutin, rifapentine, rifalazil and mixtures thereof, for treating bacterial infections of the gastrointestinal tract, in particular travellers' diarrhoea, hepatic encephalopathy, ulcerative colitis, irritable bowel syndrome (IBS), Crohn's disease, and IBD (inflammatory bowel disease) in general. Moreover, said oral administration forms allow reduction of the amounts of antibiotic to be taken, with respect to the known administration forms and without reaching blood concentrations such as to select resistant strains of tuberculosis mycobacteria.
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