首页>
外国专利>
Peptide vaccines with Seq Id No: 178, 174, 186 or 194 for cancers expressing tumor-associated antigens
Peptide vaccines with Seq Id No: 178, 174, 186 or 194 for cancers expressing tumor-associated antigens
展开▼
机译:SEQ ID NO:178、174、186或194的肽疫苗,用于表达与肿瘤相关的抗原的癌症
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention provides peptides having an amino acid sequence as set forth in SEQ ID NO: SEQ ID NO: 174, 178, 186, or 194 as well as peptides having the above-mentioned amino acid sequences in which 1, 2, or several (e.g., up to 5) amino acids are substituted, deleted, or added, provided the peptides possess cytotoxic T cell inducibility. The present invention also provides drugs for treating or preventing a disease associated with over-expression of the KIF20A, e.g. cancers containing as an active ingredient one or more of these peptides. The peptides of the present invention find further utility as vaccines.
展开▼
机译:本发明提供了具有SEQ ID NO:SEQ ID NO:174、178、186或194所示氨基酸序列的肽,以及具有上述氨基酸序列的肽,其中1、2或多个(例如,最多5个)氨基酸被取代,缺失或添加,条件是该肽具有细胞毒性T细胞诱导性。本发明还提供了用于治疗或预防与KIF20A过度表达有关的疾病的药物,例如KIF20A。含有一种或多种这些肽作为有效成分的癌症。发现本发明的肽进一步用作疫苗。
展开▼