首页>
外国专利>
TRANSLATION AND CONSTRUCTION OF NON-STANDARD PEPTIDE COMPOUND LIBRARY CONTAINING N-METHYL AMINO ACIDS AND OTHER NON-STANDARD AMINO ACIDS, AND METHOD FOR SEARCHING FOR ACTIVE SPECIES
TRANSLATION AND CONSTRUCTION OF NON-STANDARD PEPTIDE COMPOUND LIBRARY CONTAINING N-METHYL AMINO ACIDS AND OTHER NON-STANDARD AMINO ACIDS, AND METHOD FOR SEARCHING FOR ACTIVE SPECIES
展开▼
机译:包含N-甲基氨基酸和其他非标准氨基酸的非标准肽复合文库的翻译和构建,以及寻找活性物种的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
A method for screening a non-standard peptide compound in the peptide library that binds to the target substance, comprising the steps: (i) preparing a non-standard peptide library wherein a special (non-standard) amino acid is randomly incorporated into the peptide sequence by a cell-free (in vitro) translation system comprising a tRNA acylated by a special (non-standard) amino acid; (ii) bringing the obtained peptide library in contact with a target substance; and (iii) selecting a non-standard peptide that binds to the target substance as an active peptide.
展开▼