CORNEOCYTE COMPRISING FACTOR FOR MOISTURIZING, METHOD OF PRODUCING THE SAME AND COSMETIC COMPOSITION FOR MOISTURIZING WITH THE SAME

摘要

PURPOSE: A method of producing corneocyte containing a hydrogel particle containing factor for moisturizing and a lipid-coated hydrogel particle is provided to moisturize to capture water thanks to cellulase.;CONSTITUTION: Corneocyte comprises a hydrogel particle comprising a particle with factor for moisturizing and a lipid-coated hydrogel particle. Lipid is soybean lecithin, phosphatidylcholine, phosphatidylserine, phosphatidylethanolamine, phosphatidylglycol or hydrogenated phosphatidylcholine. The content of lipid is from twice to ten times the dry weight of hydrogel. The factor for moisturizing is amino acid, sodium pyrrolidone carboxylate and sodium lactate or urea. Amino acid is serine, glycine, arginine, glutamic acid, tyrosine or alanine. The content of the factor for moisturizing weighs 5-30% against corneocyte. A method of producing corneocyte comprises the following step.(a) Lipid dissolves in an organic solvent.(b) The particle for moisturizing is dispersed in the lipid dissolved solvent.(c) A hydrogel particle made of water soluble macromolecules and the water soluble crosslink agent are dispersed in the solution obtained in the step(b).(d) Water is added to the produced solution in step(c). Then, the solution produced in step(d) is decompressed and distillated. A cosmetic composition comprises corneocyte as an active ingredient.;COPYRIGHT KIPO 2013