Reporter system comprising dual promoter and methods for analyzing the differentiation of embryonic stem cells into cardiac lineage

摘要

The present invention relates to a method for detecting differentiation from multipotent stem cells to cardiac lineage cells using a reporter system for detecting single or dual promoter transcriptional activity using an Nkx2.5 promoter and an MLC2V promoter. A composition for detecting promoter activity, a kit for detecting promoter activity comprising the composition, a differentiation regulator for regulating the promoter activity, and a method for searching for the differentiation control candidate substance. ; Nkx2.5 promoter, MLC2v promoter, fluorescent reporter system, human embryonic stem cells, differentiation, myocardial system cells