METHOD FOR FABRICATING A THREE DIMENSIONAL SCAFFOLD USING KNITTING TECHNIQUE AND A SCAFFOLD THEREOF

摘要

PURPOSE: A method of fabricating three dimensional scaffolds and scaffolds therefrom are provided to easily fabricate three dimensional scaffolds with pores by utilizing biocompatible fibers and kitting technique without using a solvent, high temperature and high pressure. CONSTITUTION: A method of fabricating three dimensional scaffolds comprises: the step of preparing biocompatible fibers and a crochet hook for knitting; the step of knitting biocompatible fibers using the crochet hook so that the biocompatible fibers are able to be extended in the predetermined direction; and the step of building up in three-dimension by crossing multiple number of the knitted biocompatible fibers. The knitting step includes the step of doing the chain stitch with biocompatible fibers to the predetermined length. The knitting step includes the step of doing the double crochet or longer stitches with the chain-stitched biocompatible fibers. The width of the double crochet or longer stitches of the biocompatible fibers is determined to be half of the width of the fabricating scaffold. The three dimensional building step comprises the step preparing 4 knitted biocompatible fibers, and the step building up in three-dimension by crossing the 4 knitted biocompatible fibers with a scoubidou technique. The scoubidou technique is composed of crossing fibers so that one side of the first biocompatible fiber is adjacent to one side of the second biocompatible fiber in one direction, and the other side of the first biocompatible fiber is adjacent to the third biocompatible fiber in the other direction. The biocompatible fiber is a biocompatible thermoplastic polymer sealing fiber. The width of the biocompatible fiber is 30m-500m. The biocompatible fiber is formed with polydioxanone(PDO). [Reference numerals] (S110) Preparing a crochet hook for knitting and single fiber suitable for a living body; (S120) Knitting the single fiber suitable for a living body in a preset direction using a crochet hook for knitting; (S121) Knitting the single fiber suitable for a living body with a chain in a preset length; (S122) Shortly or long knitting the single fiber suitable for a living body with a chain; (S123) Determining the width of the shortly or longitudinally knitted single fiber half of the width of cell supporter by crossing a plurality of knitted single fibers; (S130) Piling the plurality of knitted single fibers in a three dimension by crossing the plurality of knitted single fibers; (S131) Preparing four knitted singl fiber suitable for a living body and piling the single fibers in a three dimension using a scoubidou method