PRODUCTION OF HIGHLY ISOTOPICALLY LABELLED, SECONDARY, MICROBIAL METABOLIC PRODUCTS, AND CORRESPONDING METABOLIC PRODUCTS

摘要

The present invention relates to a method for producing isotopically labeled secondary metabolic products of fungi or bacteria in liquid synthesis medium. According to this method, the synthesis is carried out by immobilizing fungi or bacteria on an inert carrier and adding a liquid synthesis medium in which essentially all carbon atoms, nitrogen atoms and / or sulfur atoms are replaced by stable isotopes.