首页> 外国专利> COMPOSITION CONTAINING A PERICARPIUM ZANTHOXYLI EXTRACT FOR PREVENTING AND TREATING OBESITY

COMPOSITION CONTAINING A PERICARPIUM ZANTHOXYLI EXTRACT FOR PREVENTING AND TREATING OBESITY

机译：包含百日咳花椒提取物的组合物，用于预防和治疗肥胖

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摘要

PURPOSE: A composition containing a Pericarpium zanthoxyli extract for preventing and treating obesity is provided to regulate OP9 cells, and to reduce lipid accumulation in a cell without cytotoxicity.;CONSTITUTION: A composition for preventing and treating obesity contains 0.1-90 parts by weight of a Pericarpium zanthoxyli extract as an active ingredient. A method for preparing the composition comprises: a step of refluxing Rubia cordifolia in an alcohol solution for 2 hours and extracting; a step of filtering the extract and concentrating by reduced pressure; a step of adding water and suspending; a step of placing the resultant at room temperature for a predetermined time; and a step of centrifuging and obtaining a water insoluble Rubia cordifolia extract.;COPYRIGHT KIPO 2013

机译：目的：提供一种包含预防和治疗肥胖症的花椒果皮提取物的组合物，以调节OP9细胞，并减少脂质在细胞中的蓄积而无细胞毒性。组成：一种用于预防和治疗肥胖症的组合物，其含量为0.1-90重量份。果皮花椒提取物作为有效成分。该组合物的制备方法包括：将茜草在醇溶液中回流2小时并萃取的步骤;和过滤提取物并减压浓缩的步骤;加水和悬浮的步骤;将所得物在室温下放置预定时间的步骤;以及离心分离和获得水不溶性茜草提取物的步骤。; COPYRIGHT KIPO 2013

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公开/公告号KR20130063690A

专利类型
公开/公告日2013-06-17

原文格式PDF
申请/专利权人 KWON KANG BEOM;MOON HYOUNG CHUL;
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申请/专利号KR20110130188
发明设计人 MOON HYOUNG CHUL;JO DONG CHAN;KWON KANG BEOM;
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申请日2011-12-07
分类号A61K36/74;A61P3/04;A61P3/00;
国家 KR
入库时间 2022-08-21 16:26:56

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Vascular304Mitophagy acts as a safeguard mechanism against human vascular smooth muscle cell apoptosis induced by atherogenic lipidsTranscriptional control and RNA species - Vascular307MicroRNA-34a role in vascular calcification308Local delivery of a miR-146a inhibitor utilizing a clinically applicable approach attenuates neointima formation after vascular injury309Long noncoding RNA landscape of hypoxic endothelial cells310Specific circulating microRNAs levels associate with hypertension, hyperglycemia and dysfunctional HDL in acute coronary syndrome patientsCytokines and cellular inflammation - Vascular313Phosphodiesterase5A up-regulation in vascular endothelium under pro-inflammatory conditions: a newly disclosed anti-inflammatory activity for the omega-3polyunsaturated aatty acid docosahexaenoic acid314Cardiovascular risk modifying with extra-low dose anticytokine drugs in rhematoid arthritis315Conversion of human M-CSF macrophages into foam cells reduces their proinflammatory responses to classical M1-polarizing activation316Lymphocytic myocarditis coincides with increased plaque inflammation and plaque hemorrhage in coronary arteries, facilitating myocardial infarction317Serum osteoprotegerin level predictsdeclined numerous of circulating endothelial- derived and mononuclear-derived progenitor cells in patients with metabolic syndromeGrowth factors and neurohormones - Vascular320Effect of gastrin-releasing peptide (GRP) on vascular inflammationSignal transduction - Heart323A new synthetic peptide regulates hypertrophy in vitro through means of the inhibition of nfkb324Inducible fibroblast-specific knockout of p38 alpha map kinase is cardioprotective in a mouse model of isoproterenol-induced cardiac hypertrophy325Regulation of beta-adrenoceptor-evoked inotropic responses by inhibitory G protein, adenylyl cyclase isoforms 5 and 6 and phosphodiesterases326Binding to RGS3 and stimulation of M2 muscarinic acetylcholine receptors modulates the substrate specificity of p190RhoGAP in cardiac myocytes327Cardiac regulation of post-translational modifications, parylation and deacetylation in LMNA dilated cardiomyopathy mouse model328Beta-adrenergic regulation of the b56delta/pp2a holoenzyme in cardiac myocytes through b56delta phosphorylation at serine 573Nitric oxide and reactive oxygen species - Vascular331Oxidative stress-induced miR-200c disrupts the regulatory loop among SIRT1, FOXO1 and eNOS332Antioxidant therapy prevents oxidative stress-induced endothelial dysfunction and Enhances Wound Healing333Morphological and biochemical characterization of red blood cell in coronary artery diseaseCytoskeleton and mechanotransduction - 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