PHARMACEUTICAL COMPOSITION FOR TREATING LUPUS NEPHRITIS COMPRISING THALIDOMIDE

摘要

PURPOSE: A pharmaceutical composition for treating lupus nephritis including thalidomide or lenalidomide is provided to prevent lupus nephritis by reducing the amount of proteinuria in a lupus nephritis animal model. CONSTITUTION: A pharmaceutical composition for treating lupus nephritis including thalidomide or lenalidomide comprises a thalidomide or a lenalidomide. The pharmaceutical composition additionally includes a corticosteroid The pharmaceutical composition additionally includes at least one selected from cyclophosphamide, and azathioprine and mycophenolate moffatt tilo. The pharmaceutical composition addtioanlly includes one of corticosteroid-based materials and cyclophosphamide, azathioprine. and mycophenolate moffatt tilo -based materials. The corticosteroid-based material is selected from prednisolone, methylprednisolone, and dexamethasone.