COMPOSITION COMPRISING CATAGEN OR TELOGEN INDUCING AGENTS FOR PREVENTING ALOPECIA INDUCED BY CANCER THERAPY AND METHOD FOR PREVENTING ALOPECIA USING THE SAME

摘要

PURPOSE: A composition for preventing or treating alopecia caused by anticancer therapy and a method for preventing or treating alopecia are provided to reduce hair follicle dystrophy and the generation of side effects, to promote primary hair recovery, and to maximize therapeutic effects by preventing and/or suppressing alopecia caused by side effects when the composition is used with anticancer therapy. CONSTITUTION: A pharmaceutical composition for preventing or treating alopecia due to chemotherapy and radiotherapy for anticancer contains one or more telogen and/or catagen inducers. The telogen or catagen inducer is selected from a group consisted of epidermal growth factor (EGF), tumor necrosis factor (TGF-beta), dexamethasone, lipid peroxide, interferon-gamma, retinoic acid, and E2 (estrogen). A method for preventing or treating alopecia caused by chemotherapy and radiotherapy for anticancer comprises the step of topically administering the one or more telogen and/or catagen inducers on patient's scalp. A method for preventing or treating alopecia caused by chemotherapy and radiotherapy for anticancer is induction of hair cell growth cycle to telogen and/or catagen.