PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING HEMATOLOGICAL MALIGNANCIES INCLUDING HEXANE EXTRACT OF GARLIC FERMENTED BY YEAST

摘要

PURPOSE: A medicinal composition for preventing or treating blood tumor is provided to enhance the expression of DR4 which is a death receptor and FasL which is a ligand specific to death receptors, to activate caspase, and to promote Bid decomposition, thereby inducing apoptosis. CONSTITUTION: A medicinal composition for preventing or treating blood tumor contains a hexane extract of yeast-fermented garlic. The blood tumor is selected among lymphoma, multiple myeloma, myeloid leukemia, and lymphoblastic leukemia. Yeast is selected among Saccharomyces cerevisiae, Saccharomyces bayanus, Saccharomyces uvarum, and Scenedesmus ellipsoideus. The hexane extract causes apoptosis in blood tumor cells.