QUALITATIVE AND QUANTITATIVE ANALYTICAL METHOD FOR ANALYZING THE ACTIVITY TYPE OF AN ENZYME THAT IS ACTIVATED BY PROTEOLYSIS

摘要

The present invention relates to a qualitative and quantitative analysis of the active form of the enzyme that is activated by proteolysis. The invention has the advantage of simple binder (e.g., antibody) by analyzing the sample within the active-type enzyme by using the enzyme-active agents, and a binder using a quick and accurate method for analyzing the activity type analysis. The present invention can be analyzed using the enzyme-active small devices than the method of analyzing the enzyme activity type present in the sample simply without complex using simple binder. The present invention can be quickly and analyzed specifically by using the inhibitor and the binding agent to the activated form of the target enzyme or enzymes at the same time, those using the characteristics of the invention drug (drug) to a high speed and large amount (high-throughput) as it can be screened. In addition, the present invention can be applied to POCT (Point of care testing) for drug administration target object (e.g., animal or human), clinical monitoring of the efficacy and dosage of the drug in the.