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Process for the differentiation of adipose-derived mesenchymal stem cells to chondrocytes and method for analyzing chondrogenic differentiation efficacy of mesenchymal stem cells

机译:脂肪来源的间充质干细胞向软骨细胞的分化过程及间充质干细胞的成软骨分化功效分析方法

摘要

The present invention comprises: (a) local to the gene encoding the TGF- receptor- derived MSCs step for switching the characteristics ; And (b) in step (a) comprises the step of culturing the mesenchymal stem cell transformed resulting in a medium for chondrocyte differentiation comprising TGF- , fat - cell differentiation into cartilage -derived mesenchymal stem cells provides a method . The present invention also provides a method of analysis of a multipotent to , mesenchymal stem cells of the chondrocyte include measuring the expression level of TGF- receptors in the MSCs . ;
机译:本发明包括:(a)在编码TGF-受体衍生的MSCs的基因局部,用于改变特征的步骤;并且(b)在步骤(a)中包括以下步骤:培养转化的间充质干细胞,产生包含TGF-的软骨细胞分化培养基,将脂肪细胞分化为软骨衍生的间充质干细胞。本发明还提供了一种对软骨细胞的间充质干细胞进行多能分析的方法,该方法包括测量MSC中TGF-受体的表达水平。 ;

著录项

  • 公开/公告号KR101287861B1

    专利类型

  • 公开/公告日2013-07-18

    原文格式PDF

  • 申请/专利权人

    申请/专利号KR20110015369

  • 申请日2011-02-22

  • 分类号C12N5/077;C12N5/0775;C12N5/02;C12N15/09;

  • 国家 KR

  • 入库时间 2022-08-21 16:24:49

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