Mycobacteria-Derived DNA Mismatch Repair Nucleotide Sequences and Uses Thereof

摘要

The present invention SEQ ID NO: 1 or SEQ ID NO: 2 for the nucleotide sequence to having mycobacterial (mycobacteria) - derived DNA Repair errors (mismatch repair) DNA nucleic acid molecule, its gene expression control sequence, and, (ⅰ) expression substance-coding nucleotide sequences; And (ⅱ) provides a recombinant vector comprising a operably linked (operatively linked) to the promoter nucleotide sequence. The nucleotide sequences of the present invention mycobacterial-DNA has a failure recovery function in the origin and MutS4AMutS4B, transformed with the mycobacterial sequence represents the resistance to UV and macrophages. Thus, the recombinant vectors of the invention gene function studies (e. G., DNA repair system error), as well as important, it can be used as a means to increase the resistance to UV and macrophages. ;