Construction of agelaxanthin A metabolic pathway and synthesis of agelaxanthin A through E.coli

摘要

The invention of E. coli for the production of rare-carotene carotenoids of azelaic xanthine A (agelaxanthin A) in nature transformants for the vector conversion, more specifically, relates to a process for producing azelaic xanthine A (agelaxanthin A) from Escherichia coli and the E. coli transformed with the vector shown in SEQ ID NO: 5 beta-carotene disae tyura dehydratase ( - carotene desaturase; CrtU) gene, and represented by SEQ ID NO: 6 beta-carotene silanol hydroxyl claim ( -carotene hydroxylase; CrtZ) for transformation vector containing the gene, and this transformed E. coli and the azelaic A from the E. coli xanthine relates to a method of production. When using a transformation vector according to the present invention can produce a hard-carotene Carcinoid A gain in the natural world of azelaic xanthine with higher efficiency than in E. coli, azelaic xanthine A produced has the advantage that can be useful in several areas. ;