GINTONIN WITH ANTI-METASTASIS ACTIVITY AND COMPOSITION CONTAINING THE GINTONIN FOR ANTI-CANCER AND ANTI-METASTASIS

摘要

PURPOSE: Gintonin which is a glycolipoprotein existing in ginseng is provided to ensure strong toxicity to cancer cells without cytotoxicity, to suppress cancer metastasis, and to prevent and treat cancer and metastasis. CONSTITUTION: Gintonin suppresses cancer metastasis by suppressing activity of autotoxin or lisophospholipase D. A composition for suppressing cancer and metastasis contains gintonin as an active ingredient. Gintonin is glycolipoprotein which is isolated and identified from ginseng. The cancer is selected among renal cell carcinoma, ovarian cancer, breast cancer, thyroid carcinoma, Hodgkin lymphomas, neuroblastoma, invasive glioblastoma multiforme, prostate cancer, and melanoma.