首页> 外国专利> APPLICATION OF 5- (AZARIDIN-1-IL) -4-HYDROXYLAMINO-2 NITROBENZAMIDE AS A MEDICINE FOR STRUGGLE AGAINST UNWANTED GROWTH OR CELL PROLIFERATION

APPLICATION OF 5- (AZARIDIN-1-IL) -4-HYDROXYLAMINO-2 NITROBENZAMIDE AS A MEDICINE FOR STRUGGLE AGAINST UNWANTED GROWTH OR CELL PROLIFERATION

机译:5-(氮杂异-1-基)-4-羟氨基-2硝基苯甲酰胺作为抗不良生长或细胞增殖的药物

摘要

1. A pharmaceutical composition comprising 5- (azaridin-1-yl) -4-hydroxylamino-2-nitrobenzamide and a pharmaceutically acceptable carrier. The use of 5- (azaridin-1-yl) -4-hydroxylamino-2-nitrobenzamide in the manufacture of a medicament for controlling undesired cell growth or proliferation in an individual. 3. The use of claim 2, wherein the unwanted growth or proliferation of cells in an individual is benign and is a wart or psoriasis, or precancerous hyperplasia. The use of claim 4, wherein the unwanted growth or proliferation of cells in an individual is neoplastic. The use according to claim 4, wherein the unwanted growth or proliferation of cells in an individual is tumor. The pharmaceutical composition according to claim 1, which is a solution or suspension containing 5- (azaridin-1-yl) -4-hydroxylamino-2-nitrobenzamide and a pharmaceutically acceptable adjuvant, diluent or carrier. A solution or suspension containing 5- (azaridin-1-yl) -4-hydroxylamino-2-nitrobenzamide and a pharmaceutically acceptable adjuvant, diluent or carrier, and which are sprayable. 8. The solution or suspension according to claim 7, used to treat cancer of the bladder, cervical cancer, ovarian cancer or brain cancer. The solution or suspension according to claim 7, used to treat cancer of the mouth, nasal cavity, throat, pharynx, larynx, trachea or lung. A mechanical nebulizer having a reservoir loaded with a solution or suspension containing 5- (azaridin-1-yl) -4-hydroxylamino-2-nitrobenzamide and a pharmaceutically acceptable adjuvant, diluent or carrier. 11. Aerosol device containing solution or �
机译:1.一种药物组合物,其包含5-(芥子碱-1-基)-4-羟基氨基-2-硝基苯甲酰胺和药学上可接受的载体。 5-(芥子碱-1-基)-4-羟基氨基-2-硝基苯甲酰胺在制造用于控制个体中不希望的细胞生长或增殖的药物中的用途。 3.权利要求2的用途,其中个体中细胞的不希望的生长或增殖是良性的,并且是疣或牛皮癣或癌前增生。 5.权利要求4的用途,其中个体中细胞的不希望的生长或增殖是赘生性的。 5.根据权利要求4的用途,其中个体中细胞的不希望的生长或增殖是肿瘤。 2.根据权利要求1所述的药物组合物,其为含有5-(芥子素-1-基)-4-羟基氨基-2-硝基苯甲酰胺和药学上可接受的佐剂,稀释剂或载体的溶液或悬浮液。含有5-(芥子碱-1-基)-4-羟基氨基-2-硝基苯甲酰胺和药学上可接受的佐剂,稀释剂或载体且可喷雾的溶液或悬浮液。 8.根据权利要求7的溶液或悬浮液,用于治疗膀胱癌,子宫颈癌,卵巢癌或脑癌。 8.根据权利要求7的溶液或悬浮液,用于治疗口腔癌,鼻腔癌,咽喉癌,咽癌,喉癌,气管癌或肺癌。一种机械雾化器,其储液器装有溶液或悬浮液,该溶液或悬浮液包含5-(芥子碱-1-基)-4-羟基氨基-2-硝基苯甲酰胺和药学上可接受的佐剂,稀释剂或载体。 11.含有溶液或的气雾剂设备。

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