SPIROCYCLIC CYCLOPROPANE AMINO ACIDS - ANALOGUES OF GAMMA-AMINOBUTYRIC ACID, WITH LIMITED CONFORMATIONAL MOBILITY AND BASED ON THEM PHARMACEUTICAL COMPOSITIONS

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention relates to novel spirocyclic cyclopropane amino acids of general formula I, demonstrating antipsychotic, antidepressant, anticonvulsant and anxiolytic properties. In formula I n = 0-3, Z = CR⁶R⁷, R¹-R⁷ represent hydrogen.;EFFECT: invention also relates to pharmaceutical composition, containing said amino acids of general formula I.;3 cl, 1 tbl, 3 ex