ENTERIC-COATED GLUCOSINOLATES AND BETA-THIOGLUCOSIDASES

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: present invention refers to a composition in the form of particles containing enteric-coated glucosinolates and beta-thioglucosidases. The present invention also represents a method for glucosinolate transformation into isothiocyanate in a small intestine providing oral introduction of an enteric-coated composition of a chemoprotector precursor containing enteric-coated glucosinolates and beta-thioglucosidases into a patient. In the other aspect, the uncoated glucosinolate and beta-tioglucosidase particles may be introduced into an enteric-coated capsule. Preferentially, glucosinolate is glucoraphanin, and beta-thioglucosodase is myrosinase.;EFFECT: enteric coating aims the compound for intestinal release wherein beta-thioglucosodase transforms glucosinolate into isothiocyanate.;29 cl, 5 dwg, 1 tbl, 2 ex