TETRAHYDROPHENANTRIDIONES AND TETRAHYDROCYCLOPENTAQUINOLINONES AS PARP INHIBITORS AND TUBULIN POLYMERISATION INHIBITORS

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: present invention refers to compounds of formula ; , ;using them as tubulin polymerisation inhibitors and PARP inhibitors, and also as an ingredient of pharmaceutical compositions containing the above compounds of formula (I), wherein R¹, R², R³, R⁴, R⁵, R⁶, R⁷ and Y have the values specified in the patent claim.;EFFECT: preparing intermediate compounds for preparing the compounds of formula (I) and a method for preparing the intermediate compounds.;16 cl, 3 tbl, 40 ex