METHOD FOR PREDICTION OF EARLY RELAPSE IN PATIENTS WITH HAEMOBLASTOSES FOLLOWING AUTOLOGOUS STEM HAEMOPOIETIC CELL TRANSPLANTATION

摘要

FIELD: medicine.;SUBSTANCE: relative CD4⁺FOXP3⁺ T-cell count in peripheral blood of the patients suffering with haemoblastoses is determined after autologous stem haemopoietic cell transplantation in a period of the lymphocyte recovery to 500 cell/mcl. If observing an increase of the CD4⁺FOXP3⁺T-raeTOK count more than 9.1%, the development of an early relapse in the post-transplantation period.;EFFECT: using the given method enables grouping the patients suffering haemoblastoses as suffering a high-risk of the development of an early relapse of the primary disease following autologous stem haemopoietic cell transplantation and in need of the additional courses of the radiation therapy and chemotherapy for the purpose of improving the efficacy of autologous stem haemopoietic cell transplantation.;4 ex