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Diagnosing malignant diseases, preferably cancer, comprises providing sample obtained from bodily fluid or bodily waste, and determining concentration of microRNA including microRNA-1246 and microRNA-1290 in the sample
Diagnosing malignant diseases, preferably cancer, comprises providing sample obtained from bodily fluid or bodily waste, and determining concentration of microRNA including microRNA-1246 and microRNA-1290 in the sample
Diagnosing malignant diseases, comprises: providing a sample obtained from a bodily fluid or a bodily waste; and determining the concentration of at least one of the microRNAs including microRNA-1246 (SEQ ID NO: 1) and microRNA-1290 (SEQ ID NO: 2), in the sample. Diagnosing malignant diseases, comprises: providing a sample obtained from a bodily fluid or a bodily waste; and determining the concentration of at least one of microRNAs including microRNA-1246 having a sequence of aauggauuuuuggagcagg (SEQ ID NO: 1) and microRNA-1290 having a sequence of uggauuuuuggaucaggga (SEQ ID NO: 2), in the sample. Independent claims are also included for: (1) a kit for diagnosing the malignant diseases, comprising at least one probe and/or a primer for detecting the microRNAs including microRNA-1246 and microRNA-1290; and (2) use of microRNA-1246 and microRNA-1290 specific probes for diagnosing cancer.
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机译:诊断恶性疾病,包括:提供从体液或身体废物获得的样品;确定样品中至少一种包括microRNA-1246(SEQ ID NO:1)和microRNA-1290(SEQ ID NO:2)的microRNA的浓度。诊断恶性疾病,包括:提供从体液或身体废物获得的样品;确定样品中至少一种微RNA的浓度,所述微RNA包括具有序列aauggauuuuuggagcagg(SEQ ID NO:1)的microRNA-1246和具有序列augauuuuuggaucaggga(SEQ ID NO:2)的microRNA-1290。还包括以下独立权利要求:(1)一种用于诊断恶性疾病的试剂盒,其包含至少一个探针和/或引物,用于检测包括microRNA-1246和microRNA-1290在内的microRNA; (2)使用microRNA-1246和microRNA-1290特异性探针诊断癌症。
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