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New growth / differentiation factor of the TGF-β family

机译:TGF-β家族的新生长/分化因子

摘要

Use of a pharmaceutical composition containing a protein encoded by a DNA sequence which comprises (a) nucleotides 1783-2142, 640-2142 or 1837-2142 of SEQ ID NO: 1, (b) any of the sequences of (a ) nucleotide sequence corresponding to the degeneracy of the genetic code, (c) an allelic derivative of a nucleotide sequence corresponding to the sequences from (a) or (b), or (d) one having one of the sequences from (a), (b) or ( c) hybridizing under stringent conditions nucleotide sequence, provided that a DNA molecule according to (d) contains at least the coding for a mature protein of the TGF-β family share, for the prevention and / or treatment of osteoporosis and / or Arthrosis.
机译:包含由DNA序列编码的蛋白质的药物组合物的用途,该DNA序列包含(a)SEQ ID NO:1的核苷酸1783-2142、640-2142或1837-2142,(b)(a)核苷酸序列的任何序列(c)对应于(a)或(b)的序列的核苷酸序列的等位基因衍生物,或(d)具有(a),(b)的序列之一的核苷酸序列的等位基因衍生物(c)在严格条件下杂交核苷酸序列,条件是根据(d)的DNA分子至少含有编码TGF-β家族成熟蛋白的编码,用于预防和/或治疗骨质疏松和/或关节。

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