首页> 外国专利> IODIZED FATTY ACID ESTERS CONTAINING AT LEAST 50 PER CENT OF MONOIODO STEARIC ACID ESTERS OR DERIVATIVES IN THE FORM OF A SOFT CAPSULE OR GELULE, USEFUL IN A NUCLEAR ACCIDENT.

IODIZED FATTY ACID ESTERS CONTAINING AT LEAST 50 PER CENT OF MONOIODO STEARIC ACID ESTERS OR DERIVATIVES IN THE FORM OF A SOFT CAPSULE OR GELULE, USEFUL IN A NUCLEAR ACCIDENT.

机译:含有至少50%的单碘硬脂酸酯或衍生物的碘化硬脂酸酯或软胶囊或胶体形式,适用于核事故。

摘要

Iodinated fatty acid esters containing not less than 50 per cent monoiodostearic acid esters of fatty acid esters of rapeseed oil, or derivatives, of pharmaceutical purity, fully iodinated, no longer containing duplicates stable bonds for the preparation of an organism protective product of drug quality either in a pure form in the form of soft capsules, capsules, or in combination with excipients in the form of soft capsule, of capsule for oral administration, useful in a nuclear accident, allowing a prolonged supply of an additional dose of iodine to the thyroid gland and in which the quantity of iodine, administered follows the recommendations of the 'World Health Organization. Thus the use of defined doses for oral administration, stable for 5 years or even 10 years at 25 ° C is recommended, or soft capsule, containing 351 mg of Brassiodol corresponding to the concentration of 100 mg of 127 |, for the child over 12 years old and adult, or soft capsule containing 175 mg of Brassiodol corresponding to the concentration of 50 mg of 127 |, for the child from 36 months to 12 years, or soft capsule containing 88 mg of Brassiodol corresponding to the concentration of 25 mg of 127 |, for the infant from 1 to 36 months. These soft Brassiodol capsules can be used by populations in regions where there is a relative lack of dietary iodine, allowing additional preventive coverage of the thyroid gland for 6 months.
机译:含碘的菜籽油脂肪酸酯或衍生物的单碘硬脂酸酯含量不少于50%的碘化脂肪酸酯,完全碘化,不再含有重复的稳定键以制备药物质量的生物保护产品以纯胶囊形式,胶囊形式或与赋形剂以软胶囊形式结合使用的口服胶囊,在核事故中有用,可延长向甲状腺的碘补充剂量根据“世界卫生组织”的建议,对腺体和碘的摄入量进行了管理。因此,对于12岁以上的孩子,建议使用规定剂量的口服剂量,在25°C稳定5年甚至10年,或使用软胶囊,其中含有351 mg的Brassiodol,相当于100 mg 127 |的浓度。岁和成人之间的关系,或对于36个月至12岁的儿童而言,含175毫克的Brassiodol的软胶囊,相当于127 |的浓度,适用于36个月至12岁的儿童,或含有88毫克的Brassiodol的软胶囊,相当于25毫克的浓度。 127 |,适用于1到36个月的婴儿。这些软的Brassiodol胶囊可被饮食中碘相对缺乏的地区的人群使用,从而可以在6个月内对甲状腺进行额外的预防性覆盖。

著录项

  • 公开/公告号FR2976491A1

    专利类型

  • 公开/公告日2012-12-21

    原文格式PDF

  • 申请/专利权人 R.I.P.H.;

    申请/专利号FR20110001814

  • 发明设计人 LOUIS JUNG;JEAN JUNG;CHRISTOPHE JUNG;

    申请日2011-06-14

  • 分类号A61K31/20;A61K31/215;

  • 国家 FR

  • 入库时间 2022-08-21 16:21:07

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