Active ingredient, preferably Lindera strychnifolia hydrolysate having specified carbohydrate content, useful in composition with cutaneous application to improve state of skin by e.g. synchronizing circadian rhythms of skin

摘要

Active ingredient, preferably Lindera strychnifolia hydrolysate comprising 40% of carbohydrates, is claimed. ACTIVITY : Nootropic; Dermatological. MECHANISM OF ACTION : Clock gene expression stimulator; Collagen I synthesis stimulator; Collagen IV synthesis stimulator; Laminin 5 synthesis stimulator. The ability of the active ingredient ( Lindera strychnifolia hydrolysate) to stimulate collagen I synthesis was tested in human fibroblast. The result showed that the percentage of collagen I stimulation was 48% at a concentration of 1%, compared to control (26%).