Diagnosis of hypertrophic cardiomyopathy from change in blood oxygen level dependent magnetic resonance signal intensity

摘要

A method of detecting hypertrophic cardiomyopathy or a gene mutation for hypertrophic cardiomyopathy is described comprising measuring the change in blood oxygen level dependent magnetic resonance signal intensity between rest and cardiac stress. Cardiac stress may be pharmacologically induced, e.g using adenosine, in the heart of a subject. Cardiac stress may alternatively be induced by physical exercise. A corresponding apparatus is also disclosed.