首页> 外国专利> PEPTIDE FOR IMPARTING TRANSITION ABILITY TO LIPID MEMBRANE STRUCTURE INTO HEPATIC ENDOTHELIAL CELL AND/OR ENHANCING THE SAME, LIPID MEMBRANE STRUCTURE HAVING TRANSITION ABILITY INTO HEPATIC ENDOTHELIAL CELL OR HAVING HAD ENHANCED TRANSITION ABILITY INTO HEPATIC ENDOTHELIAL CELL, AND AGENT FOR IMPARTING TRANSITION ABILITY TO LIPID MEMBRANE STRUCTURE INTO HEPATIC ENDOTHELIAL CELL AND/OR ENHANCING THE SAME

PEPTIDE FOR IMPARTING TRANSITION ABILITY TO LIPID MEMBRANE STRUCTURE INTO HEPATIC ENDOTHELIAL CELL AND/OR ENHANCING THE SAME, LIPID MEMBRANE STRUCTURE HAVING TRANSITION ABILITY INTO HEPATIC ENDOTHELIAL CELL OR HAVING HAD ENHANCED TRANSITION ABILITY INTO HEPATIC ENDOTHELIAL CELL, AND AGENT FOR IMPARTING TRANSITION ABILITY TO LIPID MEMBRANE STRUCTURE INTO HEPATIC ENDOTHELIAL CELL AND/OR ENHANCING THE SAME

机译:用于使脂膜结构向肝内皮细胞的转化能力提高的肽和/或增强脂蛋白膜结构向肝内皮细胞的转化能力,或使增强的迁移能力增强的人血管内皮细胞的肽能力构造成肝内皮细胞和/或增强相同的结构

摘要

PROBLEM TO BE SOLVED: To provide a peptide for imparting transition ability to a lipid membrane structure into a hepatic endothelial cell and/or enhancing the same, a lipid membrane structure having transition ability into a hepatic endothelial cell or having had enhanced transition ability into a hepatic endothelial cell, and an agent for imparting transition ability to a lipid membrane structure into a hepatic endothelial cell and/or enhancing the same.;SOLUTION: As a result of extensive research, the present inventors found that KLGR peptides and RLTR peptides impart and enhance transition ability to and of a lipid membrane structure into a hepatic endothelial cell and that a lipid membrane structure containing such as a lipid bonded to a KLGR peptide and a lipid bonded to RLTR peptide as a constituent lipid, selectively and efficiently transits into a hepatic endothelial cell.;COPYRIGHT: (C)2014,JPO&INPIT
机译:要解决的问题:提供一种肽,该肽具有将脂质膜结构转变为肝内皮细胞的能力和/或增强该脂质膜结构的脂质膜结构,该脂质膜结构具有向肝内皮细胞转变的能力或具有增强的向肝内皮细胞的转变能力的能力。肝内皮细胞,以及赋予脂质膜结构向肝内皮细胞过渡能力和/或增强其能力的药物。解决方案:本发明人作为广泛研究的结果发现,KLGR肽和RLTR肽赋予和增强了脂膜结构向肝内皮细胞的转移能力,以及包含诸如与KLGR肽键合的脂质和与RLTR肽键合的脂质作为构成脂质的脂质膜结构选择性地和有效地转移到肝细胞中的能力。内皮细胞;;版权所有:(C)2014,JPO&INPIT

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