Method of removing dibenzofulvene derivative

摘要

Deviation from protecting by reacting the amino acid chemical compound which is protected with the Fmoc basis with amine, it can, dibenzo fulvene and/or the reaction blend which includes the dibenzo fulvene amine additional mass, the polarity organic solvent which does not mix to the hydrocarbon solvent or the said hydrocarbon solvent of carbon count 5 or more (however, you exclude the amide organic solvent.)It agitates after the deviation from protecting the dibenzo fulvene which secondary forming is done and/or it is possible amount layer point, by removing hydrocarbon solvent layer among them, to select the dibenzo fulvene amine additional mass efficiently.