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MANUFACTURING METHOD OF TABLET CONTAINING CLOPIDOGREL SULFATE
MANUFACTURING METHOD OF TABLET CONTAINING CLOPIDOGREL SULFATE
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机译:含盐酸脂质脂质体的片剂的制备方法
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摘要
PROBLEM TO BE SOLVED: To provide a manufacturing method of a tablet that is a simple manufacturing method of a tablet containing clopidogrel sulfate which is unstable to water and easily generates tableting problem, the method being capable of hardly generating tableting problem, and maintaining the storage stability in a long period of time.;SOLUTION: The method comprises the step of preliminarily mixing clopidogrel sulfate with a lubricant (except for magnesium stearate) in the absence of water, adding an additive agent, and mixing and tableting them. The lubricant is preferably a hardened oil, fatty acid ester, light anhydrous silicic acid, or hydrated silicon dioxide, etc.;COPYRIGHT: (C)2014,JPO&INPIT
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