首页>
外国专利>
Magnetic resonance imaging contrast agent coated with mannan introduced with carboxyl group and method for producing the same
Magnetic resonance imaging contrast agent coated with mannan introduced with carboxyl group and method for producing the same
展开▼
机译:引入有羧基的甘露聚糖包被的磁共振成像造影剂及其制备方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
The present invention relates to a magnetic resonance imaging (MRI) contrast agent coated with carboxylated mannan, particularly a carboxylated mannan coated superparamagnetic MRI contrast agent specifically targeting antigen presenting cells and having excellent in vivo stability, and a method for producing the same. The MRI contrast agent coated with carboxylated mannan of the present invention can provide excellent in vivo stability and biocompatibility owing to its high surface negative charge, and can be introduced specifically into antigen presenting cells owing to mannose of mannan, so as to visualize the antigen presenting cells and the tissue containing the antigen presenting cells in MRI.
展开▼