IMMUNOMODULATORY PROPERTY OF MULTIPOTENT ADULT PROGENITOR CELL AND USE THEREOF

摘要

PROBLEM TO BE SOLVED: To provide compositions comprising stem cells, for adjunctive treatment of a subject at risk for or suffering from an immune dysfunction.SOLUTION: Compositions comprise cells expressing a telomerase. The cells are not embryonic stem cells, not embryonic germ cells, and not germ cells, can differentiate into at least one cell type of each of at least two of the endodermal, ectodermal, and mesodermal lineages, do not provoke a harmful immune response in a subject, are effective to treat the immune dysfunction in the subject, and are administered adjunctively to one or more other treatments administered to the subject by an effective route and in an effective amount to treat the immune dysfunction, to treat something different disease, or both. The compositions are allogeneic or xenogeneic to the subject. The cells are administered adjunctively to treat a host versus graft response to the graft.