PPROBLEM TO BE SOLVED: To provide a new pharmaceutical composition having COMT inhibiting action. PSOLUTION: The pharmaceutical composition containing a compound expressed by general formula (I) (wherein RSP3/SPrepresents halo lower alkyl, lower acyl, halo lower alkylcarbonyl, cycloalkylcarbonyl, arylcarbonyl which may be substituted, lower alkoxycarbonyl or the like; RSP4/SPrepresents lower alkyl, halo lower alkyl, cycloalkyl, lower alkoxy lower alkyl, or the like) or a pharmaceutically permissible salt thereof, and use of the same are provided. PCOPYRIGHT: (C)2011,JPO&INPIT
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