Microbial strains optimized for NADPH-consuming biosynthetic pathways

摘要

Strain (A) of microorganism that includes a deletion of at least one of the genes udhA, qor and/or pgi, provided that if (A) is a bacterium at least one of udhA and qor is deleted. Independent claims are also included for the following: (1) method for preparing (A); and (2) method for preparing a molecule of interest (I), the biosynthesis of which involves at least one NADPH-dependent reaction.