Bevacizumab and 2,2-dimethyl-N-((S) -6-oxo-6,7-dihydro-5H-dibenzo b, d azepin-7-yl) -N ′ for the treatment of proliferative diseases -(2,2,3,3,3-pentafluoro-propyl) -malonamide

摘要

The present invention relates to a combination therapy of 2,2-dimethyl-N-((S)-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl)-N-(2,2,3,3,3-pentafluoro-propyl)-malonamide, or a pharmaceutically-acceptable salt thereof, and bevacizumab for treating a patient suffering from a proliferative disorder, in particular a solid tumor, for example a brain tumor.