A method of cutting at the desired target nucleic acid using as a cutting catalyst acid (DNA, etc.) and metal ions or complex metal ions, the reaction efficiency and regioselectivity high, side reactions of (non-reactive) low, also excellent in ease and economy, I will provide a cutting method of the target nucleic acid. Method of cleaving a target nucleic acid of the present invention is a method of contacting those obtained by binding a metal complex or metal ions to a specific complex compound to the target nucleic acid, or contacting a metal complex or a metal ion complex specific compound there.
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