Compounds that can modulate or preserve the integrity of vascular endothelium for use in the prevention or treatment of acute traumatic coagulopathy and resuscitated cardiac arrest

摘要

The present invention relates to novel uses of compounds that protect the endothelium, particularly prostacyclin and variants and derivatives thereof in the treatment or prevention of acute traumatic coagulopathy (ATC) and of patients resuscitating from cardiac arrest. The invention also relates to a method of identifying individuals at risk of developing ATC.