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Using the plasma synthesis pyrrole derived polymers for neuroprotection and recombination of the central nervous system

机译:使用等离子体合成吡咯衍生的聚合物进行中枢神经系统的神经保护和重组

摘要

There are times when the fact that with in plant where purpose of this invention is semiconducting and at the same time does not have biodegradation characteristic, poly- pyrrole polyethylene glycol copolymer, iodic dope processing and the plasma in plant which is produced from the pyrrole polymer which is synthesized, has nervous protection action, induces the recombination of the spinal cord after the being damaged is stated clearly. Functional recovery of the group which uses the poly- pyrrole where at this action was proven by the model which administers the complete cutting of the spinal cord inside rut/rat, 5 times recovered in the animal which imbedded poly- pyrrole - polyethylene glycol copolymer, in comparison with the sufficient contrast group which cuts off the result and the spinal cord which appraise function completely, added, iodic doped processed was 10 times in comparison with the object group. It was verified vis-a-vis various inflammation characteristics and the immunity cell in damage place at the time of histology researching, in three experimental groups by the presence of in plant, also integration of the polymer was seen at the time of spinal nerve organizing, finally, breath characteristic, kidney characteristic or the skin characteristic infection symptom for the said bio material regarding whichever animal, either the harmful reaction or the rejection symptoms was not seen.
机译:有时,本发明的目的是在半导体中同时不具有生物降解特性的工厂中,聚吡咯聚乙二醇共聚物,碘液处理和由吡咯聚合物产生的工厂中的等离子体清楚地表明损伤后合成的具有神经保护作用的蛋白可诱导脊髓重组。使用多吡咯的小组的功能恢复得到了证实,该模型通过将车辙/大鼠内的脊髓完全切断,在植入多吡咯-聚乙二醇共聚物的动物中恢复了5倍,与截断结果的足够的造影剂组和完全评价功能的脊髓相比,添加碘掺杂处理的对象是对象组的10倍。在组织学研究时,已针对各种炎症特征和受损部位的免疫细胞进行了验证,在三个实验组中,由于存在植物,在脊髓神经组织时也观察到了聚合物的整合最后,对于任何一种动物,所述生物材料的呼吸特性,肾脏特性或皮肤特性感染症状均未发现有害反应或排斥症状。

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