PROBLEM TO BE SOLVED: To provide a method of efficiently producing a highly pure N-substituted imidazole compound, serving the purpose of saving resources as well.;SOLUTION: The method of producing a N-substituted imidazole compound including a process of distilling a mixture comprising a N-substituted imidazole compound produced by reacting N-unsubstituted imidazole compound with an alkylating agent, to fractionate the N-substituted imidazole compound, with the distilling carried out in the presence of an organic solvent having a boiling point at an atmospheric pressure in a temperature range of ±30°C relative to the boiling point at an atmospheric pressure of the N-unsubstituted imidazole compound, is characterized in that the distillate of the N-unsubstituted imidazole compound and the organic solvent distilled prior to fractionating the N-substituted imidazole compound is reused in the reaction system of the N-unsubstituted imidazole compound and the alkylating agent.;COPYRIGHT: (C)2011,JPO&INPIT
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