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Stabilization manner and the device of the arachidonic Acid which is used for the blood platelet functional assay
Stabilization manner and the device of the arachidonic Acid which is used for the blood platelet functional assay
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机译:用于血小板功能测定的花生四烯酸的稳定化方法及装置
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摘要
Methods and systems for rapidly determining the level of platelet inhibition in whole blood, due to aspirin usage and with a single use arachidonic based assay device that can be stored at ROOM temperature is provided. A lyophilized assay reagent that contains arachidonic acid at sufficient concentration to maximally activate platelets is utilized. An antioxidant within the same lyophilized assay reagent reduces the oxidation rate of arachidonic acid but does not interfere with platelet function. An oxygen absorber within the single use assay device packaging creates an inert environment within a short period of time after package is sealed. The assay device can have a housing with a plurality of channels and a common blood sample introduction port coupled to each of a channel of the plurality of channels. The assay device can also include a lyophilized assay reagent that contains arachidonic acid at sufficient concentration to maximally activate platelets.
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