Method for manufacturing a medical device for reducing platelet adhesion on a surface in contact with blood

摘要

A method of manufacturing a medical device that reduces the platelet adhesion of a surface that comes into contact with blood by irradiating at least the surface of a titanium or titanium alloy substrate that has been machined with an electron beam, and a specific pretreatment method or electron beam With this irradiation method, the adhesion of platelets on the surface that comes into contact with blood is reduced, and the formation of minute dents (so-called craters) that may occur due to electron beam irradiation is suppressed A method of manufacturing a device is provided.