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Indoline-2-one and aza-indoline-2-one

机译:Indoline-2-one和aza-indoline-2-one

摘要

The present invention relates to compounds or pharmaceutically-acceptable salts thereof, processes for preparing them, pharmaceutical compositions containing them and their use in therapy. The invention particularly relates to certain indolin-2-ones and aza-indolin-2-ones which possess anti-tumor activity and are accordingly useful in methods of treatment of the human or animal body, in particular such compounds are useful in the treatment of pathological processes which involve an aberrant cellular proliferation, such as tumor growth, rheumatoid arthritis, restenosis and atherosclerosis.
机译:本发明涉及化合物或其药学上可接受的盐,其制备方法,包含它们的药物组合物及其在治疗中的用途。本发明特别涉及某些具有抗肿瘤活性并因此可用于治疗人体或动物体的吲哚-2-酮和氮杂-吲哚-2-酮的化合物,特别是这类化合物可用于治疗人或动物的体内。涉及异常细胞增殖的病理过程,例如肿瘤生长,类风湿性关节炎,再狭窄和动脉粥样硬化。

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